Effect of aerobic exercises on circulating leucocytes in obese women with polycystic ovarian syndrome
Keywords:
Aerobic Exercises, Circulating Leucocytes, Polycystic, Ovarian, WomenAbstract
Objective: To investigate the effect of aerobic exercises on leucocytes in obese polycystic ovarian women.
Methods: Thirty obese women diagnosed with obesity and PCOS, aged 20 to 30, participated in this study from the Outpatient Clinic of Hush-Issa Central Hospital. They were randomly assigned to two equal groups: Group A, which participated in an aerobic exercise program (weight-bearing treadmill exercise) three times per week for 6 weeks alongside a diet program, and Group B, which followed only the diet program. Both groups were evaluated before and after the 6-week study by measuring weight, body mass index (BMI), waist-hip ratio, and leucocytes.
Findings: The results of this study showed a statistically significant decrease (p<0.001) in weight, BMI, and waist-hip ratio in both group (A) and group (B). A significant decrease in leucocytes was observed in group (A) (p<0.001), with no significant difference in group (B) (p>0.05). Comparisons between both groups revealed no significant difference before the study (p>0.05), but post-treatment, group (A) showed a significant decrease in weight, BMI, and WHR compared to group (B) (p<0.05). Additionally, leucocytes decreased significantly in group (A) compared to group (B) post-treatment (p<0.001).
Conclusions: It could be concluded that the aerobic exercise program was an effective method for decreasing the leucocytes in obese polycystic ovarian syndrome women.
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References
Li X, Shao R. PCOS and obesity: insulin resistance might be a common etiology for the development of type I endometrial carcinoma. Am J Cancer Res. 2014;4(1):73-79.
Azziz R, Carmina E, Chen Z, Dunaif A, Laven JS, Legro RS, et al. Polycystic ovary syndrome. Nat Rev Dis Primers. 2016;2:1–18. doi: 10.1038/nrdp.2016.57
Beavers KM, Brinkley TE, Nicklas BJ. Effect of exercise training on chronic inflammation. Clin Chim Acta. 2010;411(11-12):785-793. doi: 10.1016/j.cca.2010.02.069
Knowler D. A review of selected bioeconomic models with environmental influences in fisheries. J Bioeconomics. 2002;4(2):163-181. doi: 10.1023/A:1021151809501
Wallace AM, Sattar N. The changing role of the clinical laboratory in the investigation of polycystic ovarian syndrome. Clin Biochemist Rev. 2007;28(3):79-92.
Abazar E, Taghian F, Mardanian F, Forozandeh D. Effects of aerobic exercise on plasma lipoproteins in overweight and obese women with polycystic ovary syndrome. Adv Biomed Res. 2015;4:68-75. doi: 10.4103/2277-9175.153892
Glintborg D. Endocrine and metabolic characteristics in polycystic ovary syndrome. Dan med J. 2015;63(4):32-52.
Teede HJ, Misso ML, Costello MF, Dokras A, Laven J, Moran L, et al. International PCOS Network. Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome. Hum Reprod. 2018;33(9):1602–1618. doi: 10.1093/humrep/dey256
Covington JD, Tam CS, Pasarica M, Redman LM. Higher circulating leukocytes in women with PCOS is reversed by aerobic exercise. Biochimie. 2016;124:27-33. doi: 10.1016/j.biochi.2014.10.028
Taghavi SM, Sardar MA, Fahimeh A, Rokni H. Effect of aerobic training program on obesity and insulin resistance in young women with polycystic ovary syndrome. Iran J Diabetes Obes. 2011;3(1):41-45.
Dantas WS, das Neves W, Gil S, Barcellos CR, Rocha MP, de Sá-Pinto AL, et al. Exercise-induced anti-inflammatory effects in overweight/obese women with polycystic ovary syndrome. Cytokine. 2019;120:66-70. doi: 10.1016/j.cyto.2019.04.006
Jafari S, Taghian F. The effect of aerobic exercise training on biochemical and inflammatory markers among young females suffering from polycystic ovary syndrome. J Midwifery Reprod Health. 2020;8(2):2194-2202. doi: 10.22038/jmrh.2020.44188.1527
Vigorito C, Giallauria F, Palomba S, Cascella T, Manguso F, Lucci R, et al. Beneficial effects of a three-month structured exercise training program on cardiopulmonary functional capacity in young women with polycystic ovary syndrome. J Clin Endocrinol Metab. 2007;92(4):1379-1384. doi: 10.1210/jc.2006-2794
De Luis DA, Aller R, Izaola O, Primo D, Urdiales S, Romero E. Effects of a high-protein/low-carbohydrate diet versus a standard hypocaloric diet on weight and cardiovascular risk factors: role of a genetic variation in the rs9939609 FTO gene variant. Lifestyle Genom. 2015;8(3):128-136. doi: 10.1159/000441142
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